Central serous chorioretinopathy

Central serous chorioretinopathy (CSCR) = accumulation of subretinal fluid at the posterior pole of the fundus, ultimately leading to retinal detachment. Typically affects one eye only.  Vision becomes blurry and distorted, with objects often appearing smaller in the affected eye. May also cause difficulty with bright lights and contrast sensitivity.

Mechanism unknown, but associated with use of systemic corticosteroids, pregnancy, and Cushing’s syndrome.  Recently also been described after local corticosteroids including inhaled, intranasal, topical and periocular (!). Rare though.

Although blurred vision is a symptom of CSCR, it can be a side effect of periocular steroid treatment, as well as a symptom of whatever underlying eye condition is present (if any).

MHRA therefore says you should inform patients they should report any vision problems or disturbances.