HACEK organisms

Group of similar gram negative, low pathogenicity organisms – not actually related to each other, but cause similar infections:

  • Haemophilus (usually parainfluenzae, not H. influenzae which rarely causes endocarditis)
  • Aggregatibacter actinomycetemcomitans (prev Actinobacillus)
  • Cardiobacterium hominis
  • Eikenella corrodens
  • Kingella kingae

Commensals of the mouth – usually just cause dental infections but can cause endocarditis (gram positives are the usual cause) and osteomyelitis (esp Kingella – named after Elizabeth King – can be spread by respiratory route, so outbreaks of septic arthritis!).

May grow on chocolate agar but not the McConkey you usually use for gram negatives. Some beta-lactamase but most susceptible to cefalosporins.