Group A Streptococcus

Groups identified by Rebecca Lancefield. Group B is seen in the genitourinary tract of women and is an important pathogen in neonates. Groups C and G both cause invasive disease, both have M proteins, more common throat carriage in developing countries. Maybe also responsible for acute rheumatic fever. Alpha-haemolytic (strep viridans) are associated with line infections and endocarditis. Gamma-haemolytic include enterococci, of which faecium is usually resistant to amoxicillin but faecalis is usually sensitive. Of note, some enterococci are now resistant to vancomycin (VRE).

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