Updated November 2020 – high risk of serious developmental disorders if exposed in womb (up to 30-40% risk, including 5x higher risk of autism) and congenital malformations (10%), including:
- Spina bifida
- face/skull malformations, including cleft lip/palate
- Limb, heart, kidney, genital abnormalities
Do not prescribe to girls UNLESS other treatments ineffective or not tolerated.
Patient guide and checklist available.