Benign transient hyperphosphatasaemia

Common, typically young children with minor infections.

Due to decreased clearance, probably, carbohydrate side chains changed, affecting recognition – characteristic iso enzyme pattern on electrophoresis (ie not usual bone/liver forms).

Can be as high as 50x normal upper limit viz 10 000+!  Can last up to 6 months.

Just show that other liver function tests normal, normal calcium/phosphate and no suspicion of myositis, rickets.