Post streptococcal acute glomerulonephritis

PSAGN for short.  Develops 7-14 days post streptococcal pharyngitis, longer if pyoderma.

Classic presentation is with acute nephritis viz

  • Oliguria
  • Hypertension
  • Haematuria

which leads to fluid overload.  But can be milder eg microscopic haematuria without oliguria.

Microscopic haematuria may persist 1yr+. Acute severe hypertension can present with symptoms of visual impairment, headache, encephalopathy.  Treat with labetolol or nitroprusside infusion.

Insensible losses = 400ml/m2/d.

Less than 2% have long term haematuria or hypertension.